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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VDAC1
All Species:
38.79
Human Site:
T175
Identified Species:
65.64
UniProt:
P21796
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21796
NP_003365.1
283
30773
T175
N
F
A
V
G
Y
K
T
D
E
F
Q
L
H
T
Chimpanzee
Pan troglodytes
XP_001151901
283
30732
A175
N
F
A
V
G
Y
K
A
D
E
F
Q
L
H
P
Rhesus Macaque
Macaca mulatta
XP_001107652
283
30703
T175
N
F
A
V
G
Y
K
T
D
E
F
Q
L
H
T
Dog
Lupus familis
XP_536597
256
28121
V164
F
E
T
A
K
S
R
V
T
Q
S
N
F
V
V
Cat
Felis silvestris
Mouse
Mus musculus
Q60932
296
32333
T188
N
F
A
V
G
Y
K
T
D
E
F
Q
L
H
T
Rat
Rattus norvegicus
Q9Z2L0
283
30737
T175
N
F
A
V
G
Y
K
T
D
E
F
Q
L
H
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510394
343
37536
T188
N
F
A
V
G
Y
K
T
D
E
F
Q
L
H
T
Chicken
Gallus gallus
NP_001029041
283
30688
T175
N
F
A
V
G
Y
K
T
D
E
F
Q
L
H
T
Frog
Xenopus laevis
P81004
282
30052
T174
N
F
A
V
G
Y
K
T
G
D
F
Q
L
H
T
Zebra Danio
Brachydanio rerio
NP_001001404
283
30608
T175
N
F
A
V
G
Y
K
T
D
E
F
Q
L
H
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q94920
282
30532
T174
N
F
A
L
G
Y
T
T
K
D
F
V
L
H
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21752
283
29942
T175
S
L
A
F
G
H
S
T
P
Q
Y
T
L
H
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P04840
283
30410
A173
A
M
A
L
S
Y
F
A
K
D
Y
S
L
G
A
Red Bread Mold
Neurospora crassa
P07144
283
29981
T175
A
V
G
Y
H
A
P
T
Y
S
A
A
I
T
A
Conservation
Percent
Protein Identity:
100
98.9
99.2
86.2
N.A.
94.2
98.5
N.A.
72.3
95.4
75.6
85.5
N.A.
58.2
N.A.
40.6
N.A.
Protein Similarity:
100
98.9
99.6
87.2
N.A.
95.2
99.6
N.A.
77.2
98.2
91.8
93.6
N.A.
75.9
N.A.
60.4
N.A.
P-Site Identity:
100
86.6
100
0
N.A.
100
100
N.A.
100
100
86.6
100
N.A.
66.6
N.A.
33.3
N.A.
P-Site Similarity:
100
86.6
100
13.3
N.A.
100
100
N.A.
100
100
93.3
100
N.A.
80
N.A.
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.4
31.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47
51.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
86
8
0
8
0
15
0
0
8
8
0
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
58
22
0
0
0
0
0
% D
% Glu:
0
8
0
0
0
0
0
0
0
58
0
0
0
0
0
% E
% Phe:
8
72
0
8
0
0
8
0
0
0
72
0
8
0
0
% F
% Gly:
0
0
8
0
79
0
0
0
8
0
0
0
0
8
0
% G
% His:
0
0
0
0
8
8
0
0
0
0
0
0
0
79
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
0
8
0
65
0
15
0
0
0
0
0
0
% K
% Leu:
0
8
0
15
0
0
0
0
0
0
0
0
86
0
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
72
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
15
0
65
0
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
0
8
8
8
0
0
8
8
8
0
0
8
% S
% Thr:
0
0
8
0
0
0
8
79
8
0
0
8
0
8
65
% T
% Val:
0
8
0
65
0
0
0
8
0
0
0
8
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
79
0
0
8
0
15
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _